HCSGD entry for NR5A1

1. General information

Official gene symbolNR5A1
Entrez ID2516
Gene full namenuclear receptor subfamily 5, group A, member 1
Other gene symbolsAD4BP ELP FTZ1 FTZF1 POF7 SF-1 SF1 SPGF8 SRXY3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001553LuteinizationIEAbiological_process
GO:0003677DNA bindingIDA IEAmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003690Double-stranded DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIDAmolecular_function
GO:0003707Steroid hormone receptor activityIEAmolecular_function
GO:0003713Transcription coactivator activityTASmolecular_function
GO:0004879Ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005543Phospholipid bindingIDAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIEAbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007538Primary sex determinationTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008584Male gonad developmentIEAbiological_process
GO:0009888Tissue developmentIEAbiological_process
GO:0010259Multicellular organismal agingIEAbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0019899Enzyme bindingIPImolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0030325Adrenal gland developmentIEAbiological_process
GO:0030522Intracellular receptor signaling pathwayTASbiological_process
GO:0042445Hormone metabolic processIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEA IMPbiological_process
GO:0050810Regulation of steroid biosynthetic processTASbiological_process
GO:0051457Maintenance of protein location in nucleusIEAbiological_process
GO:2000020Positive regulation of male gonad developmentIDA IEAbiological_process
GO:2000195Negative regulation of female gonad developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61751135600.69128241330.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0702987547
GSE13712_SHEARUp0.0052612208
GSE13712_STATICUp0.1367244383
GSE19018Up0.0742813660
GSE19899_A1Down-0.0393619048
GSE19899_A2Down-0.1130232477
PubMed_21979375_A1Down-0.1001656795
PubMed_21979375_A2Down-0.0503879962
GSE35957Up0.0497675827
GSE36640Up0.0062667700
GSE54402Up0.0850054065
GSE9593Down-0.0342361515
GSE43922Up0.0297414214
GSE24585Down-0.1426832368
GSE37065Down-0.1039951735
GSE28863_A1Up0.0299004906
GSE28863_A2Down-0.1572114451
GSE28863_A3Up0.4584385976
GSE28863_A4Up0.1500346964
GSE48662Up0.1321924076

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATEDB04683 -
Phosphatidyl ethanolDB04752 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.