HCSGD entry for IL27

1. General information

Official gene symbolIL27
Entrez ID246778
Gene full nameinterleukin 27
Other gene symbolsIL-27 IL-27A IL27A IL27p28 IL30 p28
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005102Receptor bindingISSmolecular_function
GO:0005125Cytokine activityIEAmolecular_function
GO:0005615Extracellular spaceIEA ISScellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0009617Response to bacteriumIEAbiological_process
GO:0042129Regulation of T cell proliferationIEA ISSbiological_process
GO:0045078Positive regulation of interferon-gamma biosynthetic processIDAbiological_process
GO:0045087Innate immune responseIEAbiological_process
GO:0045523Interleukin-27 receptor bindingIEA ISSmolecular_function
GO:0045625Regulation of T-helper 1 cell differentiationIDAbiological_process
GO:0050688Regulation of defense response to virusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45489066140.91160741230.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0008144695
GSE13712_SHEARUp0.1010386689
GSE13712_STATICUp0.0583710392
GSE19018Up0.2999185954
GSE19899_A1Up0.0053695577
GSE19899_A2Up0.0125503023
PubMed_21979375_A1Down-0.0220381720
PubMed_21979375_A2Down-0.1388686704
GSE35957Up0.1536806648
GSE36640Up0.0704756932
GSE54402Down-0.0285802849
GSE9593Up0.0789455269
GSE43922Up0.0244253065
GSE24585Down-0.1300104113
GSE37065Up0.0431599083
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.5403272701

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017242MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.