HCSGD entry for IFIT5
1. General information
| Official gene symbol | IFIT5 |
|---|---|
| Entrez ID | 24138 |
| Gene full name | interferon-induced protein with tetratricopeptide repeats 5 |
| Other gene symbols | P58 RI58 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000049 | TRNA binding | IDA | molecular_function |
| GO:0003723 | RNA binding | IDA | molecular_function |
| GO:0003727 | Single-stranded RNA binding | IDA | molecular_function |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0032587 | Ruffle membrane | IDA | cellular_component |
| GO:0045087 | Innate immune response | IEA | biological_process |
| GO:0045177 | Apical part of cell | IDA | cellular_component |
| GO:0051607 | Defense response to virus | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1307306143 | 0.0059779872 | 0.7341498827 | 0.1562528302 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3733704942 |
| GSE13712_SHEAR | Up | 2.4015697561 |
| GSE13712_STATIC | Up | 2.0819335645 |
| GSE19018 | Down | -0.4443485440 |
| GSE19899_A1 | Down | -1.0606512591 |
| GSE19899_A2 | Down | -1.2096206039 |
| PubMed_21979375_A1 | Down | -1.8444886405 |
| PubMed_21979375_A2 | Down | -1.9865169720 |
| GSE35957 | Down | -0.5553100182 |
| GSE36640 | Up | 0.4353483152 |
| GSE54402 | Down | -0.8555976717 |
| GSE9593 | Up | 0.2676335314 |
| GSE43922 | Down | -1.2328516492 |
| GSE24585 | Down | -0.2165938874 |
| GSE37065 | Up | 0.7878262880 |
| GSE28863_A1 | Down | -0.3161280064 |
| GSE28863_A2 | Up | 0.2156888827 |
| GSE28863_A3 | Down | -0.7576388129 |
| GSE28863_A4 | Up | 0.3131344767 |
| GSE48662 | Down | -0.1195250654 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001624 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT020470 | Microarray | Functional MTI (Weak) | 17242205 |
| hsa-miR-146a-5p | MIMAT0000449 | MIRT021272 | Microarray | Functional MTI (Weak) | 18057241 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
