HCSGD entry for KIF4A
1. General information
| Official gene symbol | KIF4A |
|---|---|
| Entrez ID | 24137 |
| Gene full name | kinesin family member 4A |
| Other gene symbols | KIF4 KIF4G1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003777 | Microtubule motor activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005871 | Kinesin complex | IEA | cellular_component |
| GO:0005876 | Spindle microtubule | TAS | cellular_component |
| GO:0006996 | Organelle organization | TAS | biological_process |
| GO:0007018 | Microtubule-based movement | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0008089 | Anterograde axon cargo transport | TAS | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0016363 | Nuclear matrix | IEA | cellular_component |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0030496 | Midbody | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9816246875 | 0.0000108620 | 0.9999902473 | 0.0069833333 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.8751421460 |
| GSE13712_SHEAR | Down | -0.5101877569 |
| GSE13712_STATIC | Down | -0.8324225540 |
| GSE19018 | Down | -0.0498358637 |
| GSE19899_A1 | Down | -0.7294501211 |
| GSE19899_A2 | Down | -5.3031744794 |
| PubMed_21979375_A1 | Down | -5.4334111376 |
| PubMed_21979375_A2 | Down | -4.8181860371 |
| GSE35957 | Down | -3.6549926573 |
| GSE36640 | Down | -5.1522083040 |
| GSE54402 | Down | -1.2474463941 |
| GSE9593 | Down | -2.2686700275 |
| GSE43922 | Down | -2.3409347777 |
| GSE24585 | Up | 0.1905512138 |
| GSE37065 | Down | -0.7110013157 |
| GSE28863_A1 | Down | -0.1978990805 |
| GSE28863_A2 | Up | 0.0965225476 |
| GSE28863_A3 | Up | 0.1767698587 |
| GSE28863_A4 | Up | 0.0955852052 |
| GSE48662 | Down | -1.2042676571 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023793 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025210 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029396 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046771 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
