HCSGD entry for PRKD3
1. General information
| Official gene symbol | PRKD3 |
|---|---|
| Entrez ID | 23683 |
| Gene full name | protein kinase D3 |
| Other gene symbols | EPK2 PKC-NU PKD3 PRKCN nPKC-NU |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004697 | Protein kinase C activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0007205 | Protein kinase C-activating G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0264952775 | 0.2996379697 | 0.3794719260 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0306429572 |
| GSE13712_SHEAR | Up | 0.1511436986 |
| GSE13712_STATIC | Down | -0.0220108205 |
| GSE19018 | Down | -0.2989294345 |
| GSE19899_A1 | Up | 0.9643017025 |
| GSE19899_A2 | Up | 0.6572550372 |
| PubMed_21979375_A1 | Up | 0.8424499805 |
| PubMed_21979375_A2 | Up | 0.9813003770 |
| GSE35957 | Up | 0.0757849476 |
| GSE36640 | Down | -0.8750290137 |
| GSE54402 | Up | 0.9915683469 |
| GSE9593 | Down | -0.2303297511 |
| GSE43922 | Up | 1.2200438883 |
| GSE24585 | Down | -0.5109799526 |
| GSE37065 | Up | 0.0606449562 |
| GSE28863_A1 | Up | 0.2474118910 |
| GSE28863_A2 | Up | 0.5734441574 |
| GSE28863_A3 | Down | -0.8660304293 |
| GSE28863_A4 | Down | -0.2255271461 |
| GSE48662 | Down | -0.3256587153 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019291 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021381 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024592 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026308 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050498 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
