HCSGD entry for SH3BP4
1. General information
| Official gene symbol | SH3BP4 |
|---|---|
| Entrez ID | 23677 |
| Gene full name | SH3-domain binding protein 4 |
| Other gene symbols | BOG25 TTP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005092 | GDP-dissociation inhibitor activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005905 | Coated pit | IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | IMP | biological_process |
| GO:0010508 | Positive regulation of autophagy | IMP | biological_process |
| GO:0017016 | Ras GTPase binding | IPI | molecular_function |
| GO:0030136 | Clathrin-coated vesicle | IEA | cellular_component |
| GO:0030308 | Negative regulation of cell growth | IMP | biological_process |
| GO:0032007 | Negative regulation of TOR signaling | IMP | biological_process |
| GO:0034260 | Negative regulation of GTPase activity | IDA | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0043090 | Amino acid import | IMP | biological_process |
| GO:0050790 | Regulation of catalytic activity | IMP | biological_process |
| GO:0061462 | Protein localization to lysosome | IMP | biological_process |
| GO:0071230 | Cellular response to amino acid stimulus | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9384254778 | 0.0748955131 | 0.9999902473 | 0.5161162565 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1484094176 |
| GSE13712_SHEAR | Down | -0.2000748942 |
| GSE13712_STATIC | Up | 0.2789114809 |
| GSE19018 | Up | 0.2591050807 |
| GSE19899_A1 | Down | -0.2521123902 |
| GSE19899_A2 | Up | 0.1501380530 |
| PubMed_21979375_A1 | Down | -0.9519639759 |
| PubMed_21979375_A2 | Down | -0.0239902293 |
| GSE35957 | Down | -0.1580612033 |
| GSE36640 | Down | -0.2032065972 |
| GSE54402 | Down | -0.3394865725 |
| GSE9593 | Up | 0.0205558268 |
| GSE43922 | Down | -0.0259789087 |
| GSE24585 | Down | -0.4050668240 |
| GSE37065 | Down | -0.0717459640 |
| GSE28863_A1 | Down | -0.1954707984 |
| GSE28863_A2 | Up | 0.2974605175 |
| GSE28863_A3 | Up | 0.1263332344 |
| GSE28863_A4 | Down | -0.2635787739 |
| GSE48662 | Down | -0.1732243595 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001502 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-375 | MIMAT0000728 | MIRT019958 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024783 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025843 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026536 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038558 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041582 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048887 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
