HCSGD entry for PLXNB2
1. General information
| Official gene symbol | PLXNB2 |
|---|---|
| Entrez ID | 23654 |
| Gene full name | plexin B2 |
| Other gene symbols | MM1 Nbla00445 PLEXB2 dJ402G11.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001843 | Neural tube closure | IEA ISS | biological_process |
| GO:0001932 | Regulation of protein phosphorylation | IEA ISS | biological_process |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IEA ISS | cellular_component |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0007405 | Neuroblast proliferation | IEA ISS | biological_process |
| GO:0007420 | Brain development | IEA ISS | biological_process |
| GO:0008360 | Regulation of cell shape | IEA ISS | biological_process |
| GO:0017154 | Semaphorin receptor activity | IEA ISS | molecular_function |
| GO:0032319 | Regulation of Rho GTPase activity | IEA ISS | biological_process |
| GO:0050772 | Positive regulation of axonogenesis | IEA | biological_process |
| GO:0071526 | Semaphorin-plexin signaling pathway | ISS | biological_process |
| GO:2001222 | Regulation of neuron migration | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0298305725 | 0.9193393526 | 0.3999006619 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1159355180 |
| GSE13712_SHEAR | Down | -0.0165204444 |
| GSE13712_STATIC | Up | 0.0948428654 |
| GSE19018 | Up | 0.1615513701 |
| GSE19899_A1 | Up | 0.0063555445 |
| GSE19899_A2 | Up | 0.0812015759 |
| PubMed_21979375_A1 | Up | 0.8737560170 |
| PubMed_21979375_A2 | Up | 0.6529256919 |
| GSE35957 | Down | -0.2027250934 |
| GSE36640 | Up | 0.6225517643 |
| GSE54402 | Down | -0.9321920316 |
| GSE9593 | Up | 0.0899669421 |
| GSE43922 | Up | 0.1099304778 |
| GSE24585 | Up | 0.3195913570 |
| GSE37065 | Down | -0.0827298552 |
| GSE28863_A1 | Up | 1.2092529732 |
| GSE28863_A2 | Up | 0.6974528600 |
| GSE28863_A3 | Down | -0.0670831768 |
| GSE28863_A4 | Down | -0.0822170461 |
| GSE48662 | Up | 0.6415693639 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023196 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT024067 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039807 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043447 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT044983 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046780 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT051886 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
