HCSGD entry for NUP62

1. General information

Official gene symbolNUP62
Entrez ID23636
Gene full namenucleoporin 62kDa
Other gene symbolsIBSN SNDI p62
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0000922Spindle poleIEAcellular_component
GO:0003682Chromatin bindingNASmolecular_function
GO:0005487Nucleocytoplasmic transporter activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005635Nuclear envelopeIDA TAScellular_component
GO:0005643Nuclear poreIDA IEA ISScellular_component
GO:0005737CytoplasmNAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006351Transcription, DNA-templatedIDA ISSbiological_process
GO:0006913Nucleocytoplasmic transportNASbiological_process
GO:0007077Mitotic nuclear envelope disassemblyTASbiological_process
GO:0007166Cell surface receptor signaling pathwayIDA ISS NASbiological_process
GO:0007569Cell agingIEAbiological_process
GO:0008219Cell deathIMP ISSbiological_process
GO:0008285Negative regulation of cell proliferationIDA ISSbiological_process
GO:0008645Hexose transportTASbiological_process
GO:0009755Hormone-mediated signaling pathwayNASbiological_process
GO:0009966Regulation of signal transductionNASbiological_process
GO:0010827Regulation of glucose transportTASbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0015758Glucose transportTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0017056Structural constituent of nuclear poreIEAmolecular_function
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0030159Receptor signaling complex scaffold activityIDA ISSmolecular_function
GO:0030529Ribonucleoprotein complexIDAcellular_component
GO:0031074Nucleocytoplasmic shuttling complexNAScellular_component
GO:0031965Nuclear membraneIDA IEAcellular_component
GO:0042059Negative regulation of epidermal growth factor receptor signaling pathwayIEAbiological_process
GO:0042169SH2 domain bindingIDA ISSmolecular_function
GO:0043066Negative regulation of apoptotic processIDA ISSbiological_process
GO:0043069Negative regulation of programmed cell deathIDA ISSbiological_process
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIDA ISSbiological_process
GO:0043130Ubiquitin bindingIDA ISSmolecular_function
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0043407Negative regulation of MAP kinase activityIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045742Positive regulation of epidermal growth factor receptor signaling pathwayNASbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDA ISSbiological_process
GO:0046578Regulation of Ras protein signal transductionNASbiological_process
GO:0046580Negative regulation of Ras protein signal transductionIEAbiological_process
GO:0046930Pore complexNAScellular_component
GO:0046966Thyroid hormone receptor bindingIPI ISSmolecular_function
GO:0051028MRNA transportIEAbiological_process
GO:0051425PTB domain bindingIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94973676910.08915181790.99999024730.5665294544

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0148301549
GSE13712_SHEARDown-0.0803313126
GSE13712_STATICUp0.0898696890
GSE19018Down-0.2121215342
GSE19899_A1Down-0.3062121225
GSE19899_A2Down-0.3030754614
PubMed_21979375_A1Down-0.1515438657
PubMed_21979375_A2Down-0.3815502117
GSE35957Down-0.5864155760
GSE36640Down-1.2345930251
GSE54402Up0.1977069166
GSE9593Down-0.4338425004
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.0552832377
GSE28863_A2Up0.1544946275
GSE28863_A3Up0.2167375286
GSE28863_A4Up0.0770764386
GSE48662Down-0.1176669548

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT021011ProteomicsFunctional MTI (Weak)18668040
hsa-miR-186-5pMIMAT0000456MIRT021129SequencingFunctional MTI (Weak)20371350
hsa-miR-34a-5pMIMAT0000255MIRT025574SequencingFunctional MTI (Weak)20371350
hsa-miR-1914-5pMIMAT0007889MIRT035782CLASHFunctional MTI (Weak)23622248
hsa-miR-1224-5pMIMAT0005458MIRT036552CLASHFunctional MTI (Weak)23622248
hsa-miR-125a-3pMIMAT0004602MIRT038643CLASHFunctional MTI (Weak)23622248
hsa-miR-93-3pMIMAT0004509MIRT038819CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040077CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.