HCSGD entry for KPNA6
1. General information
| Official gene symbol | KPNA6 |
|---|---|
| Entrez ID | 23633 |
| Gene full name | karyopherin alpha 6 (importin alpha 7) |
| Other gene symbols | IPOA7 KPNA7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006606 | Protein import into nucleus | IEA | biological_process |
| GO:0006607 | NLS-bearing protein import into nucleus | TAS | biological_process |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0060135 | Maternal process involved in female pregnancy | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0571716652 | 0.9381090574 | 0.5199001727 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0896984328 |
| GSE13712_SHEAR | Up | 0.0982817461 |
| GSE13712_STATIC | Up | 0.1122345120 |
| GSE19018 | Down | -0.0146312469 |
| GSE19899_A1 | Up | 0.0993113997 |
| GSE19899_A2 | Up | 0.6644232216 |
| PubMed_21979375_A1 | Up | 0.2015910161 |
| PubMed_21979375_A2 | Up | 1.1390585616 |
| GSE35957 | Down | -0.1565935999 |
| GSE36640 | Up | 0.1430585213 |
| GSE54402 | Up | 0.1132962675 |
| GSE9593 | Up | 0.0687656021 |
| GSE43922 | Up | 0.1616539577 |
| GSE24585 | Up | 0.2017644157 |
| GSE37065 | Up | 0.0574715926 |
| GSE28863_A1 | Up | 0.5448338884 |
| GSE28863_A2 | Up | 0.6337355634 |
| GSE28863_A3 | Down | -0.5126211582 |
| GSE28863_A4 | Down | -0.3004505253 |
| GSE48662 | Up | 0.1233879304 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027429 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030446 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036872 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040104 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043939 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046703 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046883 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049058 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052349 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052621 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
