HCSGD entry for KCNE1L

1. General information

Official gene symbolKCNE1L
Entrez ID23630
Gene full nameKCNE1-like
Other gene symbolsKCNE5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005249Voltage-gated potassium channel activityIDAmolecular_function
GO:0008016Regulation of heart contractionIMPbiological_process
GO:0008076Voltage-gated potassium channel complexIDAcellular_component
GO:0015459Potassium channel regulator activityIDAmolecular_function
GO:0044325Ion channel bindingIPImolecular_function
GO:0060048Cardiac muscle contractionIMPbiological_process
GO:0060306Regulation of membrane repolarizationIDAbiological_process
GO:0060307Regulation of ventricular cardiac muscle cell membrane repolarizationIMPbiological_process
GO:0060372Regulation of atrial cardiac muscle cell membrane repolarizationIMPbiological_process
GO:0071435Potassium ion exportIDAbiological_process
GO:0071805Potassium ion transmembrane transportIDAbiological_process
GO:0086005Ventricular cardiac muscle cell action potentialIMPbiological_process
GO:0086008Voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarizationIMPmolecular_function
GO:0086013Membrane repolarization during cardiac muscle cell action potentialIMPbiological_process
GO:0086014Atrial cardiac muscle cell action potentialIMPbiological_process
GO:0086091Regulation of heart rate by cardiac conductionIMPbiological_process
GO:1901379Regulation of potassium ion transmembrane transportIDAbiological_process
GO:1901380Negative regulation of potassium ion transmembrane transportIDAbiological_process
GO:1901381Positive regulation of potassium ion transmembrane transportIDAbiological_process
GO:2001257Regulation of cation channel activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04895896430.94402654530.48742191991.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0481677588
GSE13712_SHEARUp0.5111253562
GSE13712_STATICUp0.2971890110
GSE19018Down-0.0545167246
GSE19899_A1Up0.1399358541
GSE19899_A2Up0.4216430304
PubMed_21979375_A1Up1.4672972578
PubMed_21979375_A2Up0.3027073414
GSE35957Up0.1451761708
GSE36640Down-0.2345033223
GSE54402Up0.2897575350
GSE9593Down-0.1876450655
GSE43922Up0.1684788615
GSE24585Up0.0343713145
GSE37065Up0.0936682815
GSE28863_A1Down-0.2506845203
GSE28863_A2Down-0.0174133231
GSE28863_A3Up0.5983401068
GSE28863_A4Up0.1714251733
GSE48662Down-0.1765777034

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018058MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.