HCSGD entry for MKRN2
1. General information
| Official gene symbol | MKRN2 |
|---|---|
| Entrez ID | 23609 |
| Gene full name | makorin ring finger protein 2 |
| Other gene symbols | RNF62 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4441558565 | 0.6364838722 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1002480352 |
| GSE13712_SHEAR | Up | 0.1199213804 |
| GSE13712_STATIC | Up | 0.2439300649 |
| GSE19018 | Up | 0.2947513054 |
| GSE19899_A1 | Down | -0.0288980440 |
| GSE19899_A2 | Up | 0.2173862477 |
| PubMed_21979375_A1 | Up | 0.1917976145 |
| PubMed_21979375_A2 | Down | -0.1839116078 |
| GSE35957 | Up | 0.0897822180 |
| GSE36640 | Up | 0.2900956864 |
| GSE54402 | Down | -0.1167874803 |
| GSE9593 | Up | 0.3717377700 |
| GSE43922 | Down | -0.0296263251 |
| GSE24585 | Up | 0.2938996409 |
| GSE37065 | Down | -0.0194945504 |
| GSE28863_A1 | Down | -0.0402023670 |
| GSE28863_A2 | Down | -0.2635895857 |
| GSE28863_A3 | Down | -0.6402847308 |
| GSE28863_A4 | Down | -0.0877977505 |
| GSE48662 | Down | -0.0221323139 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020253 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032377 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042305 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049766 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
