HCSGD entry for PDSS1
1. General information
| Official gene symbol | PDSS1 |
|---|---|
| Entrez ID | 23590 |
| Gene full name | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| Other gene symbols | COQ1 COQ10D2 DPS RP13-16H11.3 SPS TPRT TPT TPT 1 hDPS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000010 | Trans-hexaprenyltranstransferase activity | IDA | molecular_function |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006744 | Ubiquinone biosynthetic process | IDA IEA TAS | biological_process |
| GO:0008299 | Isoprenoid biosynthetic process | IDA IEA | biological_process |
| GO:0016740 | Transferase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IDA | molecular_function |
| GO:0050347 | Trans-octaprenyltranstransferase activity | IEA | molecular_function |
| GO:0051290 | Protein heterotetramerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5257976141 | 0.0436668516 | 0.9999902473 | 0.3930763338 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0649940266 |
| GSE13712_SHEAR | Up | 0.2775643934 |
| GSE13712_STATIC | Up | 0.1992612485 |
| GSE19018 | Down | -0.4852606032 |
| GSE19899_A1 | Up | 0.0649922842 |
| GSE19899_A2 | Down | -0.0008440380 |
| PubMed_21979375_A1 | Up | 0.9630630669 |
| PubMed_21979375_A2 | Down | -0.0166787693 |
| GSE35957 | Down | -0.6859504328 |
| GSE36640 | Down | -0.7552880446 |
| GSE54402 | Up | 0.4426078482 |
| GSE9593 | Down | -0.6105844360 |
| GSE43922 | Up | 0.2738690393 |
| GSE24585 | Down | -1.0205946395 |
| GSE37065 | Down | -0.1238181433 |
| GSE28863_A1 | Down | -0.1930344221 |
| GSE28863_A2 | Down | -0.1912167082 |
| GSE28863_A3 | Up | 0.0296057763 |
| GSE28863_A4 | Up | 0.1753361572 |
| GSE48662 | Down | -0.9075302433 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019328 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022672 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027634 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044367 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044710 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
