HCSGD entry for PADI4

1. General information

Official gene symbolPADI4
Entrez ID23569
Gene full namepeptidyl arginine deiminase, type IV
Other gene symbolsPAD PAD4 PADI5 PDI4 PDI5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004668Protein-arginine deiminase activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIDA IEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006464Cellular protein modification processIEA TASbiological_process
GO:0016568Chromatin modificationIEAbiological_process
GO:0016990Arginine deiminase activityIDAmolecular_function
GO:0018101Protein citrullinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47135837160.94571969150.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0437668699
GSE13712_SHEARUp0.0619806545
GSE13712_STATICUp0.0116871419
GSE19018Up0.2252591770
GSE19899_A1Up0.0395184222
GSE19899_A2Up0.0074233279
PubMed_21979375_A1Up0.0669777951
PubMed_21979375_A2Up0.0611665560
GSE35957Up0.0486376605
GSE36640Up0.0433089390
GSE54402Down-0.0717056099
GSE9593Up0.0441926985
GSE43922Up0.0277557086
GSE24585Up0.1228178386
GSE37065Down-0.0526787452
GSE28863_A1Down-0.0911034391
GSE28863_A2Up0.1468359018
GSE28863_A3Up0.3866076274
GSE28863_A4Up0.1525351424
GSE48662Up0.0686598990

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AzithromycinDB00207 APRD00397
N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDEDB07449 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017912MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.