HCSGD entry for PIGN
1. General information
| Official gene symbol | PIGN |
|---|---|
| Entrez ID | 23556 |
| Gene full name | phosphatidylinositol glycan anchor biosynthesis, class N |
| Other gene symbols | MCAHS MCAHS1 MCD4 MDC4 PIG-N |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005789 | Endoplasmic reticulum membrane | IEA TAS | cellular_component |
| GO:0006501 | C-terminal protein lipidation | TAS | biological_process |
| GO:0006506 | GPI anchor biosynthetic process | IEA | biological_process |
| GO:0008484 | Sulfuric ester hydrolase activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016254 | Preassembly of GPI anchor in ER membrane | TAS | biological_process |
| GO:0016740 | Transferase activity | IEA | molecular_function |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9085595950 | 0.0039899738 | 0.9999902473 | 0.1281476829 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1810503322 |
| GSE13712_SHEAR | Down | -1.2150851061 |
| GSE13712_STATIC | Down | -0.7100404016 |
| GSE19018 | Up | 0.5429415343 |
| GSE19899_A1 | Down | -0.5936615888 |
| GSE19899_A2 | Down | -1.2502664140 |
| PubMed_21979375_A1 | Down | -0.1616032489 |
| PubMed_21979375_A2 | Down | -1.0813975278 |
| GSE35957 | Up | 0.1612760457 |
| GSE36640 | Up | 0.5442669831 |
| GSE54402 | Down | -0.9811570675 |
| GSE9593 | Up | 0.0565017561 |
| GSE43922 | Down | -0.7199517926 |
| GSE24585 | Down | -0.0235641921 |
| GSE37065 | Down | -0.1441613703 |
| GSE28863_A1 | Down | -0.2087369647 |
| GSE28863_A2 | Up | 0.2491320686 |
| GSE28863_A3 | Down | -0.9640507302 |
| GSE28863_A4 | Up | 0.1221011473 |
| GSE48662 | Down | -0.2914717235 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016952 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030697 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-29b-3p | MIMAT0000100 | MIRT048378 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051603 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052542 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
