HCSGD entry for PIK3R5

1. General information

Official gene symbolPIK3R5
Entrez ID23533
Gene full namephosphoinositide-3-kinase, regulatory subunit 5
Other gene symbolsF730038I15Rik FOAP-2 P101-PI3K p101
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmISScellular_component
GO:0005829CytosolTAScellular_component
GO:0005942Phosphatidylinositol 3-kinase complexIEAcellular_component
GO:00059441-phosphatidylinositol-4-phosphate 3-kinase, class IB complexISScellular_component
GO:0006644Phospholipid metabolic processTASbiological_process
GO:0006661Phosphatidylinositol biosynthetic processTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayISSbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0014065Phosphatidylinositol 3-kinase signalingISSbiological_process
GO:0016020MembraneISScellular_component
GO:0030168Platelet activationTASbiological_process
GO:0031683G-protein beta/gamma-subunit complex bindingISSmolecular_function
GO:0043406Positive regulation of MAP kinase activityISSbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:00469351-phosphatidylinositol-3-kinase regulator activityIEAmolecular_function
GO:0051897Positive regulation of protein kinase B signalingISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65528424450.88858898980.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0477484806
GSE13712_SHEARDown-0.0069967477
GSE13712_STATICUp0.0634173575
GSE19018Up0.0614022239
GSE19899_A1Down-0.0149435628
GSE19899_A2Up0.1000794560
PubMed_21979375_A1Up0.1207551326
PubMed_21979375_A2Up0.0478815034
GSE35957Up0.2125255643
GSE36640Up0.1082580517
GSE54402Up0.2221992985
GSE9593Down-0.0365596674
GSE43922Up0.0197087776
GSE24585Up0.1333567936
GSE37065Down-0.0562918556
GSE28863_A1Down-0.0755814652
GSE28863_A2Down-0.2170628627
GSE28863_A3Up0.2487371234
GSE28863_A4Up0.0444050999
GSE48662Down-0.0185804868

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.