HCSGD entry for ZNF281
1. General information
| Official gene symbol | ZNF281 |
|---|---|
| Entrez ID | 23528 |
| Gene full name | zinc finger protein 281 |
| Other gene symbols | ZBP-99 ZNP-99 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001047 | Core promoter binding | ISS | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0003714 | Transcription corepressor activity | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0010172 | Embryonic body morphogenesis | ISS | biological_process |
| GO:0010629 | Negative regulation of gene expression | IDA IMP | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IDA | molecular_function |
| GO:0044212 | Transcription regulatory region DNA binding | IDA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA IMP | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048863 | Stem cell differentiation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9395718552 | 0.0191031534 | 0.9999902473 | 0.2707429570 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.1871613470 |
| GSE13712_SHEAR | Up | 0.3728327908 |
| GSE13712_STATIC | Up | 0.2226795674 |
| GSE19018 | Down | -0.0776781352 |
| GSE19899_A1 | Down | -0.7614316783 |
| GSE19899_A2 | Down | -0.2288619263 |
| PubMed_21979375_A1 | Down | -0.0208439610 |
| PubMed_21979375_A2 | Down | -0.1479039624 |
| GSE35957 | Up | 0.6626586905 |
| GSE36640 | Down | -0.2754567584 |
| GSE54402 | Up | 0.2227715719 |
| GSE9593 | Down | -0.4347753834 |
| GSE43922 | Up | 0.0030674643 |
| GSE24585 | Down | -0.1157579004 |
| GSE37065 | Up | 0.0205735653 |
| GSE28863_A1 | Down | -0.2325435449 |
| GSE28863_A2 | Down | -0.1711878241 |
| GSE28863_A3 | Down | -0.3153667116 |
| GSE28863_A4 | Down | -0.4477826378 |
| GSE48662 | Down | -0.6958248155 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027565 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
