HCSGD entry for CABIN1
1. General information
| Official gene symbol | CABIN1 |
|---|---|
| Entrez ID | 23523 |
| Gene full name | calcineurin binding protein 1 |
| Other gene symbols | CAIN PPP3IN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004864 | Protein phosphatase inhibitor activity | NAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007166 | Cell surface receptor signaling pathway | NAS | biological_process |
| GO:0016235 | Aggresome | IDA | cellular_component |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | NAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4521917138 | 0.3205979522 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2438028014 |
| GSE13712_SHEAR | Down | -0.1051369205 |
| GSE13712_STATIC | Down | -0.1540934767 |
| GSE19018 | Down | -0.0537531686 |
| GSE19899_A1 | Down | -0.4275638619 |
| GSE19899_A2 | Up | 0.1095260695 |
| PubMed_21979375_A1 | Down | -0.5577158158 |
| PubMed_21979375_A2 | Up | 0.5400863462 |
| GSE35957 | Down | -0.2409801407 |
| GSE36640 | Up | 0.1700073394 |
| GSE54402 | Up | 0.0523942886 |
| GSE9593 | Down | -0.1746640043 |
| GSE43922 | Up | 0.0478488660 |
| GSE24585 | Up | 0.1925487916 |
| GSE37065 | Down | -0.0628260909 |
| GSE28863_A1 | Up | 0.4707736856 |
| GSE28863_A2 | Up | 0.3874011228 |
| GSE28863_A3 | Down | -0.0240970276 |
| GSE28863_A4 | Down | -0.0276182805 |
| GSE48662 | Down | -0.1186504039 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036421 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-151a-3p | MIMAT0000757 | MIRT043612 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044682 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050262 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051109 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT051340 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 27217568 | The histone chaperone HIRA complex, consisting of histone cell cycle regulator (HIRA), Ubinuclein1 (UBN1), and calcineurin binding protein 1 (CABIN1), deposits histone variant H3 |
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