HCSGD entry for FOLR3
1. General information
| Official gene symbol | FOLR3 |
|---|---|
| Entrez ID | 2352 |
| Gene full name | folate receptor 3 (gamma) |
| Other gene symbols | FR-G FR-gamma gamma-hFR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005542 | Folic acid binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0015884 | Folic acid transport | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0019898 | Extrinsic component of membrane | TAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0006668820 | 0.9965652331 | 0.0740632911 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.0871223450 |
| GSE13712_SHEAR | Up | 0.1181774245 |
| GSE13712_STATIC | Up | 0.1639423078 |
| GSE19018 | Up | 0.1831650124 |
| GSE19899_A1 | Up | 0.3277649806 |
| GSE19899_A2 | Up | 2.1018362063 |
| PubMed_21979375_A1 | Up | 2.0186791212 |
| PubMed_21979375_A2 | Up | 1.7848364774 |
| GSE35957 | Up | 0.7281086851 |
| GSE36640 | Up | 0.5200150728 |
| GSE54402 | Up | 2.0432024235 |
| GSE9593 | Up | 0.2067379108 |
| GSE43922 | Up | 0.4806151871 |
| GSE24585 | Up | 0.0370230215 |
| GSE37065 | Up | 0.3368424540 |
| GSE28863_A1 | Down | -0.0022662396 |
| GSE28863_A2 | Down | -0.1432802369 |
| GSE28863_A3 | Up | 0.4046859046 |
| GSE28863_A4 | Up | 0.2618455959 |
| GSE48662 | Up | 0.0691981722 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| EC145 | DB05168 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20622962 | Quantitative real-time PCR validated the microarray data for selected genes: markedly increased genes were CXCL12, cadherin 6 (CDH6), and folate receptor 3 (FOLR3) |
| 20622962 | In contrast, FOLR3 mRNA expression was dramatically increased |
| 20622962 | CONCLUSION: Taken together, although a function for NPPB and FOLR3 in stem cell senescence has not been reported, our results strongly suggest that NPPB and/or FOLR3 play a significant role in the regulation of stem cell senescence |
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