HCSGD entry for HAAO
1. General information
| Official gene symbol | HAAO |
|---|---|
| Entrez ID | 23498 |
| Gene full name | 3-hydroxyanthranilate 3,4-dioxygenase |
| Other gene symbols | 3-HAO HAO |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000334 | 3-hydroxyanthranilate 3,4-dioxygenase activity | IDA IEA TAS | molecular_function |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0006569 | Tryptophan catabolic process | TAS | biological_process |
| GO:0008198 | Ferrous iron binding | IDA | molecular_function |
| GO:0009055 | Electron carrier activity | NAS | molecular_function |
| GO:0009435 | NAD biosynthetic process | IEA | biological_process |
| GO:0010043 | Response to zinc ion | IDA | biological_process |
| GO:0019805 | Quinolinate biosynthetic process | NAS | biological_process |
| GO:0019825 | Oxygen binding | IEA | molecular_function |
| GO:0031966 | Mitochondrial membrane | IEA | cellular_component |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046686 | Response to cadmium ion | IDA | biological_process |
| GO:0046874 | Quinolinate metabolic process | IEA | biological_process |
| GO:0070050 | Neuron cellular homeostasis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6124368641 | 0.6752494358 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0037919457 |
| GSE13712_SHEAR | Up | 0.0979810653 |
| GSE13712_STATIC | Down | -0.1849269027 |
| GSE19018 | Up | 0.0298319261 |
| GSE19899_A1 | Up | 0.0963697320 |
| GSE19899_A2 | Down | -0.1721529177 |
| PubMed_21979375_A1 | Down | -0.0802835976 |
| PubMed_21979375_A2 | Down | -0.0003288038 |
| GSE35957 | Down | -0.0363850575 |
| GSE36640 | Down | -0.0204673042 |
| GSE54402 | Down | -0.1801710383 |
| GSE9593 | Down | -0.2916876539 |
| GSE43922 | Up | 0.1806876447 |
| GSE24585 | Up | 0.2811641473 |
| GSE37065 | Down | -0.0500438642 |
| GSE28863_A1 | Down | -0.0797148956 |
| GSE28863_A2 | Up | 0.0114176783 |
| GSE28863_A3 | Up | 0.2518533493 |
| GSE28863_A4 | Up | 0.1168518731 |
| GSE48662 | Up | 0.1685820041 |

