HCSGD entry for HAAO


1. General information

Official gene symbolHAAO
Entrez ID23498
Gene full name3-hydroxyanthranilate 3,4-dioxygenase
Other gene symbols3-HAO HAO
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00003343-hydroxyanthranilate 3,4-dioxygenase activityIDA IEA TASmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005829CytosolIDA TAScellular_component
GO:0006569Tryptophan catabolic processTASbiological_process
GO:0008198Ferrous iron bindingIDAmolecular_function
GO:0009055Electron carrier activityNASmolecular_function
GO:0009435NAD biosynthetic processIEAbiological_process
GO:0010043Response to zinc ionIDAbiological_process
GO:0019805Quinolinate biosynthetic processNASbiological_process
GO:0019825Oxygen bindingIEAmolecular_function
GO:0031966Mitochondrial membraneIEAcellular_component
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046686Response to cadmium ionIDAbiological_process
GO:0046874Quinolinate metabolic processIEAbiological_process
GO:0070050Neuron cellular homeostasisIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.61243686410.67524943580.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0037919457
GSE13712_SHEARUp0.0979810653
GSE13712_STATICDown-0.1849269027
GSE19018Up0.0298319261
GSE19899_A1Up0.0963697320
GSE19899_A2Down-0.1721529177
PubMed_21979375_A1Down-0.0802835976
PubMed_21979375_A2Down-0.0003288038
GSE35957Down-0.0363850575
GSE36640Down-0.0204673042
GSE54402Down-0.1801710383
GSE9593Down-0.2916876539
GSE43922Up0.1806876447
GSE24585Up0.2811641473
GSE37065Down-0.0500438642
GSE28863_A1Down-0.0797148956
GSE28863_A2Up0.0114176783
GSE28863_A3Up0.2518533493
GSE28863_A4Up0.1168518731
GSE48662Up0.1685820041

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.