HCSGD entry for PES1
1. General information
| Official gene symbol | PES1 |
|---|---|
| Entrez ID | 23481 |
| Gene full name | pescadillo ribosomal biogenesis factor 1 |
| Other gene symbols | PES |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000463 | Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | IEA IMP | biological_process |
| GO:0000466 | Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | IEA IMP | biological_process |
| GO:0000793 | Condensed chromosome | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | IDA IEA | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA IEA | cellular_component |
| GO:0006364 | RRNA processing | IEA IMP | biological_process |
| GO:0007000 | Nucleolus organization | IEA | biological_process |
| GO:0008283 | Cell proliferation | IMP NAS | biological_process |
| GO:0030687 | Preribosome, large subunit precursor | IDA IEA | cellular_component |
| GO:0033365 | Protein localization to organelle | IEA | biological_process |
| GO:0042254 | Ribosome biogenesis | IEA | biological_process |
| GO:0042273 | Ribosomal large subunit biogenesis | IC | biological_process |
| GO:0043021 | Ribonucleoprotein complex binding | IEA | molecular_function |
| GO:0051726 | Regulation of cell cycle | IMP | biological_process |
| GO:0070545 | PeBoW complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3062329775 | 0.7349389803 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2075120652 |
| GSE13712_SHEAR | Down | -0.0630539135 |
| GSE13712_STATIC | Down | -0.0029729010 |
| GSE19018 | Down | -0.0051939124 |
| GSE19899_A1 | Up | 0.0277510664 |
| GSE19899_A2 | Up | 0.1552250107 |
| PubMed_21979375_A1 | Up | 0.2533526656 |
| PubMed_21979375_A2 | Up | 0.2794306407 |
| GSE35957 | Down | -0.1156912254 |
| GSE36640 | Down | -0.0374265211 |
| GSE54402 | Up | 0.1124109570 |
| GSE9593 | Down | -0.1384414523 |
| GSE43922 | Up | 0.1226093407 |
| GSE24585 | Down | -0.7356332305 |
| GSE37065 | Down | -0.1906936374 |
| GSE28863_A1 | Up | 0.3547737120 |
| GSE28863_A2 | Up | 0.1369975445 |
| GSE28863_A3 | Down | -0.0490767057 |
| GSE28863_A4 | Up | 0.1842116999 |
| GSE48662 | Up | 0.1867031411 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022851 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028562 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051556 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
