HCSGD entry for QPRT
1. General information
| Official gene symbol | QPRT |
|---|---|
| Entrez ID | 23475 |
| Gene full name | quinolinate phosphoribosyltransferase |
| Other gene symbols | QPRTase |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004514 | Nicotinate-nucleotide diphosphorylase (carboxylating) activity | IDA IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0009435 | NAD biosynthetic process | IEA | biological_process |
| GO:0019674 | NAD metabolic process | TAS | biological_process |
| GO:0034213 | Quinolinate catabolic process | IDA | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051259 | Protein oligomerization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1401574826 | 0.9321512936 | 0.7524138487 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0792423245 |
| GSE13712_SHEAR | Up | 0.0185546151 |
| GSE13712_STATIC | Up | 0.0167819375 |
| GSE19018 | Down | -0.0207209335 |
| GSE19899_A1 | Up | 0.1035647416 |
| GSE19899_A2 | Up | 0.1192779885 |
| PubMed_21979375_A1 | Down | -0.3485321637 |
| PubMed_21979375_A2 | Down | -0.0413066587 |
| GSE35957 | Up | 0.0462942154 |
| GSE36640 | Up | 1.1770699413 |
| GSE54402 | Up | 0.1855331846 |
| GSE9593 | Up | 0.8076246261 |
| GSE43922 | Down | -0.2897445988 |
| GSE24585 | Up | 0.0066318845 |
| GSE37065 | Up | 0.2418100682 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.4439297720 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017727 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029367 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036528 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042601 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
