HCSGD entry for GCAT
1. General information
| Official gene symbol | GCAT |
|---|---|
| Entrez ID | 23464 |
| Gene full name | glycine C-acetyltransferase |
| Other gene symbols | KBL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0006520 | Cellular amino acid metabolic process | NAS | biological_process |
| GO:0008890 | Glycine C-acetyltransferase activity | NAS | molecular_function |
| GO:0009058 | Biosynthetic process | IEA | biological_process |
| GO:0019518 | L-threonine catabolic process to glycine | IEA | biological_process |
| GO:0030170 | Pyridoxal phosphate binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8726133582 | 0.0664327571 | 0.9999902473 | 0.4861208229 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4069784898 |
| GSE13712_SHEAR | Down | -0.4360668289 |
| GSE13712_STATIC | Down | -0.5871777559 |
| GSE19018 | Up | 0.2692281982 |
| GSE19899_A1 | Down | -0.8053109704 |
| GSE19899_A2 | Down | -0.4054614052 |
| PubMed_21979375_A1 | Down | -0.2486261736 |
| PubMed_21979375_A2 | Down | -0.9530908932 |
| GSE35957 | Down | -0.3430090144 |
| GSE36640 | Up | 0.1161115564 |
| GSE54402 | Up | 0.1608548567 |
| GSE9593 | Down | -0.2496990219 |
| GSE43922 | Up | 0.0378621036 |
| GSE24585 | Up | 0.2082295917 |
| GSE37065 | Down | -0.2485753490 |
| GSE28863_A1 | Down | -0.2597602471 |
| GSE28863_A2 | Down | -0.1913936859 |
| GSE28863_A3 | Up | 0.1482737437 |
| GSE28863_A4 | Up | 0.1076178544 |
| GSE48662 | Down | -0.2175066969 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Glycine | DB00145 | NUTR00028 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-3p | MIMAT0004509 | MIRT038791 | CLASH | Functional MTI (Weak) | 23622248 |
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