HCSGD entry for ABCA5
1. General information
| Official gene symbol | ABCA5 |
|---|---|
| Entrez ID | 23461 |
| Gene full name | ATP-binding cassette, sub-family A (ABC1), member 5 |
| Other gene symbols | ABC13 EST90625 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005764 | Lysosome | IEA ISS | cellular_component |
| GO:0005765 | Lysosomal membrane | IEA | cellular_component |
| GO:0005770 | Late endosome | IEA ISS | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0010745 | Negative regulation of macrophage derived foam cell differentiation | IEA ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016887 | ATPase activity | IEA | molecular_function |
| GO:0031902 | Late endosome membrane | IEA | cellular_component |
| GO:0033344 | Cholesterol efflux | IEA ISS | biological_process |
| GO:0034375 | High-density lipoprotein particle remodeling | IEA ISS | biological_process |
| GO:0043691 | Reverse cholesterol transport | IC | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3691877246 | 0.0824396565 | 0.9999902473 | 0.5436135169 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0849300025 |
| GSE13712_SHEAR | Up | 0.2537497674 |
| GSE13712_STATIC | Up | 0.8321339509 |
| GSE19018 | Down | -0.4118959859 |
| GSE19899_A1 | Down | -0.0624531499 |
| GSE19899_A2 | Down | -0.9002613691 |
| PubMed_21979375_A1 | Down | -0.6966632396 |
| PubMed_21979375_A2 | Down | -0.4289397604 |
| GSE35957 | Down | -0.1611358322 |
| GSE36640 | Up | 0.2495933203 |
| GSE54402 | Down | -0.3034909720 |
| GSE9593 | Down | -0.3244869637 |
| GSE43922 | Down | -0.1147246868 |
| GSE24585 | Up | 1.1207719716 |
| GSE37065 | Down | -0.0628506519 |
| GSE28863_A1 | Up | 0.0014689019 |
| GSE28863_A2 | Up | 0.1281075126 |
| GSE28863_A3 | Down | -0.3548108942 |
| GSE28863_A4 | Down | -0.1454545949 |
| GSE48662 | Up | 0.1430351682 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017298 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
