HCSGD entry for ANGPTL2


1. General information

Official gene symbolANGPTL2
Entrez ID23452
Gene full nameangiopoietin-like 2
Other gene symbolsARP2 HARP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005102Receptor bindingTASmolecular_function
GO:0005615Extracellular spaceTAScellular_component
GO:0007275Multicellular organismal developmentTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03094663200.01921710800.40727315000.2708311064

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1357100788
GSE13712_SHEARDown-0.1682137912
GSE13712_STATICDown-0.8082305534
GSE19018Down-0.6036163579
GSE19899_A1Down-0.4092146156
GSE19899_A2Down-0.7666327153
PubMed_21979375_A1Down-0.9811844046
PubMed_21979375_A2Up0.6296362597
GSE35957Down-1.0191104240
GSE36640Up2.0476646656
GSE54402Down-1.3373063730
GSE9593Up0.7495944356
GSE43922Down-0.6153237946
GSE24585Up0.2126070980
GSE37065Up0.5928001417
GSE28863_A1Up1.0141499025
GSE28863_A2Up1.4922916620
GSE28863_A3Up0.1182453729
GSE28863_A4Down-0.1946718770
GSE48662Up0.3068841669

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

19011671EC exhibited higher expression levels of markers of oxidative stress (lipid peroxydation level and caveolin-1 mRNA), inflammation (angiopoietin-like 2 mRNA), hypoxia (vascular endothelial growth factor (VEGF)-A mRNA), and cell damage (p53 mRNA)
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