HCSGD entry for HARS2
1. General information
| Official gene symbol | HARS2 |
|---|---|
| Entrez ID | 23438 |
| Gene full name | histidyl-tRNA synthetase 2, mitochondrial |
| Other gene symbols | HARSL HARSR HO3 PRLTS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004812 | Aminoacyl-tRNA ligase activity | IEA | molecular_function |
| GO:0004821 | Histidine-tRNA ligase activity | IEA NAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006412 | Translation | NAS | biological_process |
| GO:0006418 | TRNA aminoacylation for protein translation | IEA TAS | biological_process |
| GO:0006427 | Histidyl-tRNA aminoacylation | IEA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9417036625 | 0.0568073439 | 0.9999902473 | 0.4474859707 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3725564543 |
| GSE13712_SHEAR | Up | 0.2241059639 |
| GSE13712_STATIC | Down | -0.0779621042 |
| GSE19018 | Down | -0.4911013630 |
| GSE19899_A1 | Down | -0.1180002142 |
| GSE19899_A2 | Down | -0.5596724583 |
| PubMed_21979375_A1 | Down | -0.1985486409 |
| PubMed_21979375_A2 | Down | -0.5157989991 |
| GSE35957 | Down | -0.7331614830 |
| GSE36640 | Down | -0.2736264998 |
| GSE54402 | Down | -0.1570895698 |
| GSE9593 | Down | -0.3370792559 |
| GSE43922 | Up | 0.0499698675 |
| GSE24585 | Down | -0.1211882093 |
| GSE37065 | Up | 0.2387606751 |
| GSE28863_A1 | Up | 0.1485974310 |
| GSE28863_A2 | Up | 0.2315629417 |
| GSE28863_A3 | Down | -0.5254023002 |
| GSE28863_A4 | Down | -0.2267751387 |
| GSE48662 | Down | -0.3416898085 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT001459 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042251 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
