HCSGD entry for RHOQ


1. General information

Official gene symbolRHOQ
Entrez ID23433
Gene full nameras homolog family member Q
Other gene symbolsARHQ RASL7A TC10 TC10A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003924GTPase activityIDAmolecular_function
GO:0005522Profilin bindingIPImolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005884Actin filamentIDAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006184GTP catabolic processIDAbiological_process
GO:0007264Small GTPase mediated signal transductionIEA TASbiological_process
GO:0008286Insulin receptor signaling pathwayIMPbiological_process
GO:0008360Regulation of cell shapeIEAbiological_process
GO:0030866Cortical actin cytoskeleton organizationIEA IMPbiological_process
GO:0032427GBD domain bindingIPImolecular_function
GO:0032869Cellular response to insulin stimulusIEA IMPbiological_process
GO:0032956Regulation of actin cytoskeleton organizationICbiological_process
GO:0045121Membrane raftIEAcellular_component
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046326Positive regulation of glucose importIMPbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0051491Positive regulation of filopodium assemblyIDAbiological_process
GO:0090005Negative regulation of establishment of protein localization to plasma membraneIEA IMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28077454880.30835492190.97828512641.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0371702910
GSE13712_SHEARUp0.3641724174
GSE13712_STATICUp0.2861392985
GSE19018Up0.5062139473
GSE19899_A1Down-0.5733655508
GSE19899_A2Up0.2929502167
PubMed_21979375_A1Down-0.8124654056
PubMed_21979375_A2Down-0.0787977642
GSE35957Up0.1465424516
GSE36640Up0.4763701267
GSE54402Down-0.3689535356
GSE9593Up0.7598176186
GSE43922Down-0.6440584982
GSE24585Down-0.2450770940
GSE37065Up0.0278426001
GSE28863_A1Down-0.1628533424
GSE28863_A2Up0.1571527721
GSE28863_A3Down-0.1351453099
GSE28863_A4Up0.0524649969
GSE48662Up0.2455935254

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017580MicroarrayFunctional MTI (Weak)18185580
hsa-miR-375MIMAT0000728MIRT019764MicroarrayFunctional MTI (Weak)20215506
hsa-miR-21-5pMIMAT0000076MIRT030813MicroarrayFunctional MTI (Weak)18591254
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.