HCSGD entry for SLC7A8

1. General information

Official gene symbolSLC7A8
Entrez ID23428
Gene full namesolute carrier family 7 (amino acid transporter light chain, L system), member 8
Other gene symbolsLAT2 LPI-PC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006520Cellular amino acid metabolic processTASbiological_process
GO:0006810TransportTASbiological_process
GO:0006811Ion transportTASbiological_process
GO:0006812Cation transportIDAbiological_process
GO:0006865Amino acid transportIDA TASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0009636Response to toxic substanceNASbiological_process
GO:0015101Organic cation transmembrane transporter activityIDAmolecular_function
GO:0015171Amino acid transmembrane transporter activityEXP IDA IEA ISSmolecular_function
GO:0015175Neutral amino acid transmembrane transporter activityTASmolecular_function
GO:0015179L-amino acid transmembrane transporter activityIEAmolecular_function
GO:0015695Organic cation transportIDAbiological_process
GO:0015804Neutral amino acid transportISSbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016323Basolateral plasma membraneIEAcellular_component
GO:0019534Toxin transporter activityIDAmolecular_function
GO:0042605Peptide antigen bindingISSmolecular_function
GO:0050900Leukocyte migrationTASbiological_process
GO:0055065Metal ion homeostasisNASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:1901998Toxin transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11313609290.62545609970.69241999531.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0086475931
GSE13712_SHEARDown-0.6324520236
GSE13712_STATICDown-0.2423668052
GSE19018Down-0.0447179636
GSE19899_A1Down-0.0800505778
GSE19899_A2Up0.1327987461
PubMed_21979375_A1Up0.0799718942
PubMed_21979375_A2Down-0.0536740833
GSE35957Down-0.0301144900
GSE36640Up0.2160487401
GSE54402Up0.2037539441
GSE9593Up0.1858718003
GSE43922Up0.1603102179
GSE24585Up0.8957748240
GSE37065Up0.7941652040
GSE28863_A1Up0.1156632109
GSE28863_A2Up0.7506285293
GSE28863_A3Down-0.7367348341
GSE28863_A4Up0.0837500805
GSE48662Down-0.0006653476

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-PhenylalanineDB00120 NUTR00044
L-AlanineDB00160 NUTR00013

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.