HCSGD entry for MLYCD


1. General information

Official gene symbolMLYCD
Entrez ID23417
Gene full namemalonyl-CoA decarboxylase
Other gene symbolsMCD
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002931Response to ischemiaISSbiological_process
GO:0005102Receptor bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005759Mitochondrial matrixISScellular_component
GO:0005777PeroxisomeIDAcellular_component
GO:0005782Peroxisomal matrixISS TAScellular_component
GO:0006085Acetyl-CoA biosynthetic processIDA IEAbiological_process
GO:0006633Fatty acid biosynthetic processIDAbiological_process
GO:0010906Regulation of glucose metabolic processIMPbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046321Positive regulation of fatty acid oxidationIMPbiological_process
GO:0050080Malonyl-CoA decarboxylase activityIDAmolecular_function
GO:2001294Malonyl-CoA catabolic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47860316100.77927940810.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0784370519
GSE13712_SHEARDown-0.4017003469
GSE13712_STATICDown-0.1504283509
GSE19018Down-0.0401641441
GSE19899_A1Up0.0152371038
GSE19899_A2Up0.5564689936
PubMed_21979375_A1Up0.2593947167
PubMed_21979375_A2Up0.2670900916
GSE35957Down-0.0241072389
GSE36640Up0.2077260960
GSE54402Up0.0614408603
GSE9593Up0.0971775425
GSE43922Up0.0100722946
GSE24585Up0.0492632210
GSE37065Down-0.0230590054
GSE28863_A1Up0.0228025190
GSE28863_A2Down-0.2891641160
GSE28863_A3Up0.1868974806
GSE28863_A4Up0.0507696662
GSE48662Up0.2426103206

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017783MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.