HCSGD entry for KCNH3
1. General information
| Official gene symbol | KCNH3 |
|---|---|
| Entrez ID | 23416 |
| Gene full name | potassium voltage-gated channel, subfamily H (eag-related), member 3 |
| Other gene symbols | BEC1 ELK2 Kv12.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000155 | Phosphorelay sensor kinase activity | IEA | molecular_function |
| GO:0005249 | Voltage-gated potassium channel activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IBA | cellular_component |
| GO:0006813 | Potassium ion transport | TAS | biological_process |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0042391 | Regulation of membrane potential | IBA | biological_process |
| GO:0071805 | Potassium ion transmembrane transport | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2426579423 | 0.9022950306 | 0.9299221123 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0547153862 |
| GSE13712_SHEAR | Up | 0.2683790020 |
| GSE13712_STATIC | Down | -0.0546218630 |
| GSE19018 | Up | 0.0301051431 |
| GSE19899_A1 | Down | -0.0254171966 |
| GSE19899_A2 | Up | 0.0498976200 |
| PubMed_21979375_A1 | Down | -0.2843603701 |
| PubMed_21979375_A2 | Up | 0.1918577692 |
| GSE35957 | Up | 0.3179848008 |
| GSE36640 | Down | -0.0571818045 |
| GSE54402 | Up | 0.0919088004 |
| GSE9593 | Up | 0.1519559774 |
| GSE43922 | Up | 0.0614573433 |
| GSE24585 | Down | -0.1845873335 |
| GSE37065 | Down | -0.1404873456 |
| GSE28863_A1 | Down | -0.0221752894 |
| GSE28863_A2 | Up | 0.0050222850 |
| GSE28863_A3 | Up | 0.3995549964 |
| GSE28863_A4 | Up | 0.0962924062 |
| GSE48662 | Up | 0.9155369815 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016741 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
