HCSGD entry for ZFPM2
1. General information
| Official gene symbol | ZFPM2 |
|---|---|
| Entrez ID | 23414 |
| Gene full name | zinc finger protein, FOG family member 2 |
| Other gene symbols | DIH3 FOG2 ZC2HC11B ZNF89B hFOG-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0001071 | Nucleic acid binding transcription factor activity | IEA | molecular_function |
| GO:0001105 | RNA polymerase II transcription coactivator activity | NAS | molecular_function |
| GO:0001570 | Vasculogenesis | IEA | biological_process |
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0003148 | Outflow tract septum morphogenesis | IMP | biological_process |
| GO:0003221 | Right ventricular cardiac muscle tissue morphogenesis | IMP | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003714 | Transcription corepressor activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | NAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008134 | Transcription factor binding | IEA IPI | molecular_function |
| GO:0008270 | Zinc ion binding | NAS | molecular_function |
| GO:0030324 | Lung development | IEA | biological_process |
| GO:0045599 | Negative regulation of fat cell differentiation | IEA IMP | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048568 | Embryonic organ development | IEA | biological_process |
| GO:0048738 | Cardiac muscle tissue development | IEA | biological_process |
| GO:0060412 | Ventricular septum morphogenesis | IMP | biological_process |
| GO:0060548 | Negative regulation of cell death | IEA | biological_process |
| GO:2000020 | Positive regulation of male gonad development | IEA | biological_process |
| GO:2000195 | Negative regulation of female gonad development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9922063371 | 0.0000085939 | 0.9999902473 | 0.0069833333 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -2.2793395830 |
| GSE13712_SHEAR | Down | -1.4252101293 |
| GSE13712_STATIC | Down | -0.6718935062 |
| GSE19018 | Down | -0.4810138008 |
| GSE19899_A1 | Down | -4.9617157507 |
| GSE19899_A2 | Down | -4.9967532232 |
| PubMed_21979375_A1 | Down | -4.0194769912 |
| PubMed_21979375_A2 | Down | -6.9591360449 |
| GSE35957 | Up | 0.2937605653 |
| GSE36640 | Down | -0.9363657921 |
| GSE54402 | Down | -2.8421135770 |
| GSE9593 | Up | 0.1108044933 |
| GSE43922 | Down | -2.3012986487 |
| GSE24585 | Down | -0.7975974415 |
| GSE37065 | Up | 0.8144116226 |
| GSE28863_A1 | Down | -0.0203637138 |
| GSE28863_A2 | Down | -0.2561394449 |
| GSE28863_A3 | Down | -0.4271592237 |
| GSE28863_A4 | Down | -0.2351417770 |
| GSE48662 | Down | -0.4678789812 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-141-3p | MIMAT0000432 | MIRT004621 | Luciferase reporter assay//Western blot//Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200a-3p | MIMAT0000682 | MIRT004622 | Luciferase reporter assay//Western blot//Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200b-3p | MIMAT0000318 | MIRT004623 | Luciferase reporter assay//Western blot//Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200c-3p | MIMAT0000617 | MIRT004624 | Luciferase reporter assay//Western blot//Reporter assay | Functional MTI | 20005803 |
| hsa-miR-429 | MIMAT0001536 | MIRT004625 | Luciferase reporter assay//Western blot//Reporter assay | Functional MTI | 20005803 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028872 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-200a-3p | MIMAT0000682 | NA | hsa-miR-200a | 20005803 | |||
| hsa-miR-200b-3p | MIMAT0000318 | NA | hsa-miR-200b | 20005803 | |||
| hsa-miR-429 | MIMAT0001536 | NA | hsa-miR-429 | 20005803 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
