HCSGD entry for COTL1
1. General information
| Official gene symbol | COTL1 |
|---|---|
| Entrez ID | 23406 |
| Gene full name | coactosin-like 1 (Dictyostelium) |
| Other gene symbols | CLP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0019899 | Enzyme binding | IEA IPI | molecular_function |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0050832 | Defense response to fungus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1188128339 | 0.0874468333 | 0.7070870684 | 0.5608082095 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1714341488 |
| GSE13712_SHEAR | Up | 0.4015449423 |
| GSE13712_STATIC | Up | 0.1516762538 |
| GSE19018 | Down | -0.4968613549 |
| GSE19899_A1 | Down | -0.0398135791 |
| GSE19899_A2 | Up | 1.0171650759 |
| PubMed_21979375_A1 | Up | 0.5030364147 |
| PubMed_21979375_A2 | Up | 0.6260284393 |
| GSE35957 | Down | -0.4827239570 |
| GSE36640 | Up | 1.6601107757 |
| GSE54402 | Up | 0.1315840834 |
| GSE9593 | Up | 0.2830364363 |
| GSE43922 | Down | -0.1049052348 |
| GSE24585 | Up | 0.1756920476 |
| GSE37065 | Down | -0.4864451134 |
| GSE28863_A1 | Down | -0.3251611891 |
| GSE28863_A2 | Down | -0.7577315997 |
| GSE28863_A3 | Up | 0.1043642308 |
| GSE28863_A4 | Down | -0.1543734532 |
| GSE48662 | Down | -0.9777744964 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016551 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-1 | MIMAT0000416 | MIRT024011 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037467 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043571 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044527 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
