HCSGD entry for SMG5
1. General information
| Official gene symbol | SMG5 |
|---|---|
| Entrez ID | 23381 |
| Gene full name | smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) |
| Other gene symbols | EST1B LPTS-RP1 LPTSRP1 SMG-5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0035303 | Regulation of dephosphorylation | IMP | biological_process |
| GO:0051721 | Protein phosphatase 2A binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0511324266 | 0.7836336347 | 0.4953465587 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0735288737 |
| GSE13712_SHEAR | Up | 0.4449746124 |
| GSE13712_STATIC | Up | 0.2394776765 |
| GSE19018 | Down | -0.3882854470 |
| GSE19899_A1 | Up | 0.1808006346 |
| GSE19899_A2 | Up | 0.5142717148 |
| PubMed_21979375_A1 | Up | 1.3675717826 |
| PubMed_21979375_A2 | Up | 1.0109557193 |
| GSE35957 | Down | -0.1801130443 |
| GSE36640 | Up | 0.3675958233 |
| GSE54402 | Up | 0.2526236871 |
| GSE9593 | Up | 0.0506227119 |
| GSE43922 | Up | 0.3732445862 |
| GSE24585 | Down | -0.3669073895 |
| GSE37065 | Up | 0.0387457815 |
| GSE28863_A1 | Down | -0.0801846935 |
| GSE28863_A2 | Up | 0.3765785664 |
| GSE28863_A3 | Down | -0.5456491964 |
| GSE28863_A4 | Down | -0.3083634839 |
| GSE48662 | Up | 0.2905224812 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-708-5p | MIMAT0004926 | MIRT037745 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038311 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-3p | MIMAT0004672 | MIRT038568 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041477 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043281 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
