HCSGD entry for RRP8
1. General information
| Official gene symbol | RRP8 |
|---|---|
| Entrez ID | 23378 |
| Gene full name | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
| Other gene symbols | KIAA0409 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000183 | Chromatin silencing at rDNA | IDA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005677 | Chromatin silencing complex | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006364 | RRNA processing | IEA | biological_process |
| GO:0008168 | Methyltransferase activity | IEA | molecular_function |
| GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | TAS | molecular_function |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0033553 | RDNA heterochromatin | IDA | cellular_component |
| GO:0035064 | Methylated histone residue binding | IDA | molecular_function |
| GO:0042149 | Cellular response to glucose starvation | IMP | biological_process |
| GO:0046015 | Regulation of transcription by glucose | IMP | biological_process |
| GO:0071158 | Positive regulation of cell cycle arrest | IMP | biological_process |
| GO:0072332 | Intrinsic apoptotic signaling pathway by p53 class mediator | IMP | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6302976711 | 0.6857250978 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0469090823 |
| GSE13712_SHEAR | Up | 0.0731587534 |
| GSE13712_STATIC | Up | 0.0975936731 |
| GSE19018 | Down | -0.0954859257 |
| GSE19899_A1 | Up | 0.0860752954 |
| GSE19899_A2 | Up | 0.2579260364 |
| PubMed_21979375_A1 | Up | 0.3683464410 |
| PubMed_21979375_A2 | Up | 0.0158743810 |
| GSE35957 | Up | 0.0146527194 |
| GSE36640 | Up | 0.0284923016 |
| GSE54402 | Up | 0.1984376671 |
| GSE9593 | Down | -0.1806497991 |
| GSE43922 | Up | 0.1366682201 |
| GSE24585 | Down | -0.3807726606 |
| GSE37065 | Down | -0.0975628012 |
| GSE28863_A1 | Up | 0.1579207228 |
| GSE28863_A2 | Up | 0.0204386438 |
| GSE28863_A3 | Down | -0.2029874887 |
| GSE28863_A4 | Down | -0.0026242040 |
| GSE48662 | Up | 0.0032815612 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT005242 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
