HCSGD entry for CRTC1
1. General information
| Official gene symbol | CRTC1 |
|---|---|
| Entrez ID | 23373 |
| Gene full name | CREB regulated transcription coactivator 1 |
| Other gene symbols | MECT1 TORC-1 TORC1 WAMTP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008140 | CAMP response element binding protein binding | IDA | molecular_function |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0032793 | Positive regulation of CREB transcription factor activity | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0051289 | Protein homotetramerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5325851487 | 0.8009588162 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0712141300 |
| GSE13712_SHEAR | Down | -0.0883195141 |
| GSE13712_STATIC | Down | -0.0209325014 |
| GSE19018 | Down | -0.0740447615 |
| GSE19899_A1 | Down | -0.1004514730 |
| GSE19899_A2 | Up | 0.2391658970 |
| PubMed_21979375_A1 | Down | -0.0131151063 |
| PubMed_21979375_A2 | Up | 0.0187424214 |
| GSE35957 | Up | 0.1384489133 |
| GSE36640 | Up | 0.0678703916 |
| GSE54402 | Down | -0.0258618874 |
| GSE9593 | Up | 0.0188630952 |
| GSE43922 | Up | 0.0410189510 |
| GSE24585 | Up | 0.1230339004 |
| GSE37065 | Down | -0.1633860167 |
| GSE28863_A1 | Down | -0.1050765860 |
| GSE28863_A2 | Down | -0.0417088178 |
| GSE28863_A3 | Up | 0.3724194550 |
| GSE28863_A4 | Up | 0.1051790730 |
| GSE48662 | Up | 0.5256847663 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045900 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
