HCSGD entry for UBR4
1. General information
| Official gene symbol | UBR4 |
|---|---|
| Entrez ID | 23352 |
| Gene full name | ubiquitin protein ligase E3 component n-recognin 4 |
| Other gene symbols | RBAF600 ZUBR1 p600 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0488133810 | 0.9732404658 | 0.4868918151 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0835977182 |
| GSE13712_SHEAR | Up | 0.2615039643 |
| GSE13712_STATIC | Up | 0.1153251499 |
| GSE19018 | Up | 0.3222024628 |
| GSE19899_A1 | Up | 0.1657423224 |
| GSE19899_A2 | Up | 0.1847748505 |
| PubMed_21979375_A1 | Up | 0.0854858451 |
| PubMed_21979375_A2 | Up | 0.3791814023 |
| GSE35957 | Down | -0.0046318297 |
| GSE36640 | Up | 0.1561403412 |
| GSE54402 | Up | 0.0714789168 |
| GSE9593 | Up | 0.0570684354 |
| GSE43922 | Up | 0.3326347854 |
| GSE24585 | Up | 0.2699446565 |
| GSE37065 | Up | 0.2054192296 |
| GSE28863_A1 | Up | 0.7849963234 |
| GSE28863_A2 | Up | 0.4551430940 |
| GSE28863_A3 | Down | -0.0023776176 |
| GSE28863_A4 | Down | -0.3952546082 |
| GSE48662 | Down | -0.0346832333 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020486 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021907 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025219 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037028 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037272 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038352 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-5p | MIMAT0000731 | MIRT043973 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045339 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050176 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
