HCSGD entry for DOCK9
1. General information
| Official gene symbol | DOCK9 |
|---|---|
| Entrez ID | 23348 |
| Gene full name | dedicator of cytokinesis 9 |
| Other gene symbols | ZIZ1 ZIZIMIN1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005089 | Rho guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0012505 | Endomembrane system | IEA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0017048 | Rho GTPase binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0325074465 | 0.9076994795 | 0.4163752798 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0599130582 |
| GSE13712_SHEAR | Up | 0.2856895378 |
| GSE13712_STATIC | Down | -0.2197918208 |
| GSE19018 | Down | -0.0816631616 |
| GSE19899_A1 | Up | 0.1843466236 |
| GSE19899_A2 | Up | 0.8465929763 |
| PubMed_21979375_A1 | Up | 1.5933524608 |
| PubMed_21979375_A2 | Up | 1.2561924251 |
| GSE35957 | Up | 0.1755633712 |
| GSE36640 | Down | -0.0256129517 |
| GSE54402 | Up | 0.1832912129 |
| GSE9593 | Up | 0.4061245608 |
| GSE43922 | Up | 0.7785364609 |
| GSE24585 | Down | -0.0924530545 |
| GSE37065 | Up | 0.1080665872 |
| GSE28863_A1 | Down | -0.0355760736 |
| GSE28863_A2 | Down | -0.1831053881 |
| GSE28863_A3 | Down | -0.2373136241 |
| GSE28863_A4 | Up | 0.1375380954 |
| GSE48662 | Down | -0.0742058360 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017247 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028250 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051177 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
