HCSGD entry for CLASP1

1. General information

Official gene symbolCLASP1
Entrez ID23332
Gene full namecytoplasmic linker associated protein 1
Other gene symbolsMAST1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000226Microtubule cytoskeleton organizationIGIbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000776KinetochoreIDAcellular_component
GO:0000777Condensed chromosome kinetochoreIEAcellular_component
GO:0001578Microtubule bundle formationIMPbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005794Golgi apparatusIDAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005828Kinetochore microtubuleIEA TAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005876Spindle microtubuleIDAcellular_component
GO:0005881Cytoplasmic microtubuleIDA IEAcellular_component
GO:0005938Cell cortexIDAcellular_component
GO:0007020Microtubule nucleationIMPbiological_process
GO:0007026Negative regulation of microtubule depolymerizationIEA IGI IMPbiological_process
GO:0007163Establishment or maintenance of cell polarityNASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008017Microtubule bindingIDA IMPmolecular_function
GO:0010458Exit from mitosisIMPbiological_process
GO:0030981Cortical microtubule cytoskeletonIDAcellular_component
GO:0031023Microtubule organizing center organizationIMPbiological_process
GO:0031111Negative regulation of microtubule polymerization or depolymerizationIMPbiological_process
GO:0031592Centrosomal coronaIDAcellular_component
GO:0034453Microtubule anchoringIMPbiological_process
GO:0043515Kinetochore bindingIEA IMPmolecular_function
GO:0051010Microtubule plus-end bindingIDA IEAmolecular_function
GO:0051294Establishment of spindle orientationIDA IGI IMPbiological_process
GO:0051301Cell divisionIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.30091501080.44875270700.99954366481.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1338933979
GSE13712_SHEARUp0.1203840063
GSE13712_STATICDown-0.1626362260
GSE19018Up0.1765991248
GSE19899_A1Down-0.1064536449
GSE19899_A2Down-0.4128651170
PubMed_21979375_A1Down-0.1215749488
PubMed_21979375_A2Up0.3565474519
GSE35957Up0.2568666687
GSE36640Up0.0927863125
GSE54402Down-0.1036059717
GSE9593Up0.1780843003
GSE43922Down-0.1160083665
GSE24585Up0.0602404147
GSE37065Up0.1193299968
GSE28863_A1Up0.5449427384
GSE28863_A2Up0.6873853007
GSE28863_A3Down-0.2820895983
GSE28863_A4Down-0.4184002597
GSE48662Up0.1933588870

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031634ProteomicsFunctional MTI (Weak)18668040
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.