HCSGD entry for SATB2
1. General information
| Official gene symbol | SATB2 |
|---|---|
| Entrez ID | 23314 |
| Gene full name | SATB homeobox 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000118 | Histone deacetylase complex | IEA | cellular_component |
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0001764 | Neuron migration | IEA | biological_process |
| GO:0002076 | Osteoblast development | IEA | biological_process |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005667 | Transcription factor complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006338 | Chromatin remodeling | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0009880 | Embryonic pattern specification | IEA | biological_process |
| GO:0016363 | Nuclear matrix | IEA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0048704 | Embryonic skeletal system morphogenesis | IEA | biological_process |
| GO:0051216 | Cartilage development | IEA | biological_process |
| GO:0060021 | Palate development | IEA | biological_process |
| GO:0071310 | Cellular response to organic substance | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6154562441 | 0.2153378937 | 0.9999902473 | 0.8951825154 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1218498475 |
| GSE13712_SHEAR | Down | -0.2915346672 |
| GSE13712_STATIC | Down | -0.1779355949 |
| GSE19018 | Down | -0.1497603732 |
| GSE19899_A1 | Up | 0.1212342254 |
| GSE19899_A2 | Down | -0.1823174554 |
| PubMed_21979375_A1 | Up | 0.2444996271 |
| PubMed_21979375_A2 | Up | 0.0260646291 |
| GSE35957 | Down | -0.8889396020 |
| GSE36640 | Up | 0.4819507362 |
| GSE54402 | Up | 0.5470116165 |
| GSE9593 | Down | -0.2231784504 |
| GSE43922 | Down | -0.0016467639 |
| GSE24585 | Up | 0.0767880991 |
| GSE37065 | Up | 0.3601529457 |
| GSE28863_A1 | Down | -0.0691068645 |
| GSE28863_A2 | Up | 0.0719630849 |
| GSE28863_A3 | Down | -0.2360390979 |
| GSE28863_A4 | Down | -0.2949010906 |
| GSE48662 | Down | -0.2956168609 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-31-5p | MIMAT0000089 | MIRT006567 | Luciferase reporter assay | Functional MTI | 20980827 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025532 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026761 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-320b | MIMAT0005792 | MIRT036228 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-5p | MIMAT0004776 | MIRT037950 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044745 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045505 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
