HCSGD entry for UBR2

1. General information

Official gene symbolUBR2
Entrez ID23304
Gene full nameubiquitin protein ligase E3 component n-recognin 2
Other gene symbolsC6orf133 RP3-392M17.3 bA49A4.1 dJ242G1.1 dJ392M17.3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000151Ubiquitin ligase complexIEAcellular_component
GO:0000785ChromatinIEAcellular_component
GO:0004842Ubiquitin-protein ligase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006342Chromatin silencingISSbiological_process
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0007141Male meiosis IIEAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0032007Negative regulation of TOR signalingIMPbiological_process
GO:0033522Histone H2A ubiquitinationISSbiological_process
GO:0070728Leucine bindingIDAmolecular_function
GO:0071233Cellular response to leucineIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47002740020.26587318490.99999024730.9877273253

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0315440861
GSE13712_SHEARDown-0.0010519621
GSE13712_STATICUp0.0638275145
GSE19018Up0.1420576812
GSE19899_A1Down-0.1828686922
GSE19899_A2Down-0.0773165847
PubMed_21979375_A1Down-0.6263047828
PubMed_21979375_A2Down-0.0048089929
GSE35957Up0.0049148839
GSE36640Up0.3099492228
GSE54402Down-0.1701641054
GSE9593Up0.0624405964
GSE43922Down-0.0865938554
GSE24585Up0.0631497538
GSE37065Up0.2343370253
GSE28863_A1Up0.5124178868
GSE28863_A2Up0.7876826854
GSE28863_A3Down-0.7383033539
GSE28863_A4Down-0.3096709920
GSE48662Down-0.1274412967

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017640MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.