HCSGD entry for FMO3
1. General information
| Official gene symbol | FMO3 |
|---|---|
| Entrez ID | 2328 |
| Gene full name | flavin containing monooxygenase 3 |
| Other gene symbols | FMOII TMAU dJ127D3.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004499 | N,N-dimethylaniline monooxygenase activity | IEA TAS | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA TAS | cellular_component |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016597 | Amino acid binding | IEA | molecular_function |
| GO:0017144 | Drug metabolic process | IEA | biological_process |
| GO:0034899 | Trimethylamine monooxygenase activity | IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050660 | Flavin adenine dinucleotide binding | IEA | molecular_function |
| GO:0050661 | NADP binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0656240796 | 0.1738308499 | 0.5520180511 | 0.8073529723 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0854692547 |
| GSE13712_SHEAR | Down | -0.0785433004 |
| GSE13712_STATIC | Down | -0.0284876387 |
| GSE19018 | Down | -0.2743313692 |
| GSE19899_A1 | Up | 0.0292653740 |
| GSE19899_A2 | Down | -0.1625498229 |
| PubMed_21979375_A1 | Up | 0.0122671222 |
| PubMed_21979375_A2 | Up | 0.0155938303 |
| GSE35957 | Down | -1.1666597033 |
| GSE36640 | Down | -0.1199773859 |
| GSE54402 | Down | -0.0986687164 |
| GSE9593 | Up | 0.6739458429 |
| GSE43922 | Up | 0.0136828369 |
| GSE24585 | Up | 0.0816819943 |
| GSE37065 | Down | -0.4595851108 |
| GSE28863_A1 | Up | 0.6063295436 |
| GSE28863_A2 | Up | 1.5230955891 |
| GSE28863_A3 | Up | 0.1083993684 |
| GSE28863_A4 | Up | 0.0821298488 |
| GSE48662 | Up | 0.2987377929 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030320 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
