HCSGD entry for MCF2L

1. General information

Official gene symbolMCF2L
Entrez ID23263
Gene full nameMCF.2 cell line derived transforming sequence-like
Other gene symbolsARHGEF14 DBS OST
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:00055451-phosphatidylinositol bindingIEAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0007266Rho protein signal transductionIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0030027LamellipodiumIEAcellular_component
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0043065Positive regulation of apoptotic processTASbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76071760570.66524176890.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0124223884
GSE13712_SHEARDown-0.0096842995
GSE13712_STATICUp0.0283099835
GSE19018Up0.0017343404
GSE19899_A1Up0.0770473337
GSE19899_A2Up0.0968880106
PubMed_21979375_A1Down-0.1543959247
PubMed_21979375_A2Down-0.1230483369
GSE35957Up0.1302262330
GSE36640Up0.0167916963
GSE54402Down-0.0411066732
GSE9593Down-0.0741349918
GSE43922Up0.0376039581
GSE24585Up0.0817270134
GSE37065Down-0.0492793885
GSE28863_A1Up0.0183641983
GSE28863_A2Down-0.3309667899
GSE28863_A3Up0.3929723220
GSE28863_A4Down-0.0277241200
GSE48662Down-0.0347092579

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.