HCSGD entry for FLT3LG
1. General information
| Official gene symbol | FLT3LG |
|---|---|
| Entrez ID | 2323 |
| Gene full name | fms-related tyrosine kinase 3 ligand |
| Other gene symbols | FL FLT3L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IDA IEA | biological_process |
| GO:0016020 | Membrane | IEA NAS | cellular_component |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0030098 | Lymphocyte differentiation | IEA | biological_process |
| GO:0030971 | Receptor tyrosine kinase binding | IEA | molecular_function |
| GO:0031233 | Intrinsic component of external side of plasma membrane | IEA | cellular_component |
| GO:0032825 | Positive regulation of natural killer cell differentiation | IEA | biological_process |
| GO:0035162 | Embryonic hemopoiesis | IDA | biological_process |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7835081532 | 0.1948346719 | 0.9999902473 | 0.8553733167 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1088231778 |
| GSE13712_SHEAR | Down | -0.2083697849 |
| GSE13712_STATIC | Up | 0.0977005329 |
| GSE19018 | Down | -0.0664635303 |
| GSE19899_A1 | Down | -0.0753601765 |
| GSE19899_A2 | Down | -0.1962455359 |
| PubMed_21979375_A1 | Down | -0.6287678052 |
| PubMed_21979375_A2 | Down | -0.4086519098 |
| GSE35957 | Down | -0.3466115898 |
| GSE36640 | Down | -0.1127206375 |
| GSE54402 | Down | -0.1867040701 |
| GSE9593 | Up | 0.2230982656 |
| GSE43922 | Down | -0.0551479042 |
| GSE24585 | Up | 0.1393474196 |
| GSE37065 | Up | 0.2974632531 |
| GSE28863_A1 | Up | 0.2516750286 |
| GSE28863_A2 | Up | 0.0044631255 |
| GSE28863_A3 | Up | 0.2579400300 |
| GSE28863_A4 | Down | -0.0165455672 |
| GSE48662 | Up | 0.2554161683 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
