HCSGD entry for TBC1D1
1. General information
| Official gene symbol | TBC1D1 |
|---|---|
| Entrez ID | 23216 |
| Gene full name | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| Other gene symbols | TBC TBC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005097 | Rab GTPase activator activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0032880 | Regulation of protein localization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9195794233 | 0.1664984499 | 0.9999902473 | 0.7890918452 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0988266316 |
| GSE13712_SHEAR | Down | -0.3630224113 |
| GSE13712_STATIC | Down | -0.1540614427 |
| GSE19018 | Up | 0.2339112783 |
| GSE19899_A1 | Down | -0.2996653209 |
| GSE19899_A2 | Up | 0.1063971947 |
| PubMed_21979375_A1 | Up | 0.3237883716 |
| PubMed_21979375_A2 | Down | -0.0038983297 |
| GSE35957 | Down | -0.1820195079 |
| GSE36640 | Down | -0.3758381524 |
| GSE54402 | Up | 0.2756727989 |
| GSE9593 | Up | 0.0772747971 |
| GSE43922 | Up | 0.0003345634 |
| GSE24585 | Down | -0.1455289828 |
| GSE37065 | Up | 0.1623142376 |
| GSE28863_A1 | Down | -0.1858106158 |
| GSE28863_A2 | Down | -0.3022201214 |
| GSE28863_A3 | Down | -0.1496753702 |
| GSE28863_A4 | Down | -0.1535645955 |
| GSE48662 | Down | -0.0760603441 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125b-5p | MIMAT0000423 | MIRT006523 | Luciferase reporter assay | Functional MTI | 19635812 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016481 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-7-1-3p | MIMAT0004553 | MIRT038677 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT045726 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
