HCSGD entry for PMPCA
1. General information
| Official gene symbol | PMPCA |
|---|---|
| Entrez ID | 23203 |
| Gene full name | peptidase (mitochondrial processing) alpha |
| Other gene symbols | Alpha-MPP INPP5E |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004222 | Metalloendopeptidase activity | IEA TAS | molecular_function |
| GO:0005739 | Mitochondrion | IDA IEA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0005759 | Mitochondrial matrix | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA TAS | biological_process |
| GO:0006626 | Protein targeting to mitochondrion | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0083958816 | 0.9167903385 | 0.2370178270 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5011808255 |
| GSE13712_SHEAR | Up | 0.2125317382 |
| GSE13712_STATIC | Up | 0.2795635167 |
| GSE19018 | Down | -0.1660988100 |
| GSE19899_A1 | Up | 1.0798575838 |
| GSE19899_A2 | Up | 1.2635675511 |
| PubMed_21979375_A1 | Up | 2.0570394414 |
| PubMed_21979375_A2 | Up | 1.5566143189 |
| GSE35957 | Down | -0.1204347459 |
| GSE36640 | Down | -0.0084232168 |
| GSE54402 | Up | 0.5575729189 |
| GSE9593 | Down | -0.2909168241 |
| GSE43922 | Up | 0.8693472234 |
| GSE24585 | Down | -0.3066860268 |
| GSE37065 | Down | -0.2016282358 |
| GSE28863_A1 | Up | 0.0601152533 |
| GSE28863_A2 | Down | -0.1087299311 |
| GSE28863_A3 | Down | -0.0013961328 |
| GSE28863_A4 | Up | 0.0954104119 |
| GSE48662 | Up | 0.0212032935 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028878 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038065 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051702 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
