HCSGD entry for ATP11B
1. General information
| Official gene symbol | ATP11B |
|---|---|
| Entrez ID | 23200 |
| Gene full name | ATPase, class VI, type 11B |
| Other gene symbols | ATPIF ATPIR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0004012 | Phospholipid-translocating ATPase activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005637 | Nuclear inner membrane | NAS | cellular_component |
| GO:0005769 | Early endosome | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006200 | ATP catabolic process | TAS | biological_process |
| GO:0006811 | Ion transport | NAS | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0015075 | Ion transmembrane transporter activity | NAS | molecular_function |
| GO:0015917 | Aminophospholipid transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019829 | Cation-transporting ATPase activity | IEA | molecular_function |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0045332 | Phospholipid translocation | NAS | biological_process |
| GO:0055037 | Recycling endosome | IDA | cellular_component |
| GO:0055038 | Recycling endosome membrane | IEA | cellular_component |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2774607386 | 0.2462328407 | 0.9745188284 | 0.9549434526 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2372682510 |
| GSE13712_SHEAR | Up | 0.5619353529 |
| GSE13712_STATIC | Up | 0.2476252796 |
| GSE19018 | Up | 0.1546800953 |
| GSE19899_A1 | Down | -0.0375987928 |
| GSE19899_A2 | Up | 0.7242603255 |
| PubMed_21979375_A1 | Up | 0.0152481940 |
| PubMed_21979375_A2 | Up | 0.3615889800 |
| GSE35957 | Up | 0.3693101405 |
| GSE36640 | Down | -0.4088626375 |
| GSE54402 | Down | -0.0884998477 |
| GSE9593 | Up | 0.0221451559 |
| GSE43922 | Up | 0.0060395664 |
| GSE24585 | Up | 0.3626252471 |
| GSE37065 | Down | -0.1304394506 |
| GSE28863_A1 | Down | -0.0384056701 |
| GSE28863_A2 | Up | 0.2741087456 |
| GSE28863_A3 | Down | -0.7059028716 |
| GSE28863_A4 | Down | -0.2676084744 |
| GSE48662 | Down | -0.4120569930 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030997 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-652-3p | MIMAT0003322 | MIRT039507 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046578 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
