HCSGD entry for ATG4B
1. General information
| Official gene symbol | ATG4B |
|---|---|
| Entrez ID | 23192 |
| Gene full name | autophagy related 4B, cysteine peptidase |
| Other gene symbols | APG4B AUTL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000045 | Autophagic vacuole assembly | IGI | biological_process |
| GO:0004175 | Endopeptidase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA ISS | cellular_component |
| GO:0006508 | Proteolysis | IDA IEA | biological_process |
| GO:0006914 | Autophagy | IEA IGI | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IDA IEA | molecular_function |
| GO:0010508 | Positive regulation of autophagy | IDA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0045732 | Positive regulation of protein catabolic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0120091144 | 0.9967616314 | 0.2739097920 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2645977955 |
| GSE13712_SHEAR | Down | -0.0783491976 |
| GSE13712_STATIC | Down | -0.0421201112 |
| GSE19018 | Up | 0.2660862624 |
| GSE19899_A1 | Up | 0.1330630678 |
| GSE19899_A2 | Up | 0.7383408009 |
| PubMed_21979375_A1 | Up | 1.3073030682 |
| PubMed_21979375_A2 | Up | 0.6132785432 |
| GSE35957 | Up | 0.0844964321 |
| GSE36640 | Up | 0.3920045350 |
| GSE54402 | Up | 0.2873818034 |
| GSE9593 | Down | -0.0288198970 |
| GSE43922 | Up | 0.2325330886 |
| GSE24585 | Up | 0.1696537348 |
| GSE37065 | Up | 0.1056770436 |
| GSE28863_A1 | Up | 0.3142496912 |
| GSE28863_A2 | Up | 0.2886458294 |
| GSE28863_A3 | Up | 0.3082508863 |
| GSE28863_A4 | Up | 0.2626834078 |
| GSE48662 | Up | 0.4271839664 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT032363 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
