HCSGD entry for FLNB
1. General information
| Official gene symbol | FLNB |
|---|---|
| Entrez ID | 2317 |
| Gene full name | filamin B, beta |
| Other gene symbols | ABP-278 ABP-280 AOI FH1 FLN-B FLN1L LRS1 SCT TABP TAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001725 | Stress fiber | IEA | cellular_component |
| GO:0003779 | Actin binding | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005925 | Focal adhesion | IEA | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0007016 | Cytoskeletal anchoring at plasma membrane | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007519 | Skeletal muscle tissue development | IEA | biological_process |
| GO:0015629 | Actin cytoskeleton | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0030018 | Z disc | IEA | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | TAS | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0296181908 | 0.1432243570 | 0.3981513790 | 0.7288879157 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.4405248259 |
| GSE13712_SHEAR | Up | 0.1388035257 |
| GSE13712_STATIC | Up | 0.0283018194 |
| GSE19018 | Up | 0.7287864317 |
| GSE19899_A1 | Up | 0.2382386503 |
| GSE19899_A2 | Up | 0.6001335710 |
| PubMed_21979375_A1 | Up | 0.7580112839 |
| PubMed_21979375_A2 | Up | 1.0356948322 |
| GSE35957 | Down | -1.1859881327 |
| GSE36640 | Down | -0.3120280784 |
| GSE54402 | Up | 0.1777884392 |
| GSE9593 | Down | -1.7317146858 |
| GSE43922 | Up | 0.8556704971 |
| GSE24585 | Up | 0.1022024852 |
| GSE37065 | Down | -1.0070170808 |
| GSE28863_A1 | Up | 0.4503838974 |
| GSE28863_A2 | Up | 0.3372941502 |
| GSE28863_A3 | Down | -0.0994508287 |
| GSE28863_A4 | Down | -0.1035487394 |
| GSE48662 | Up | 0.1697791349 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020752 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021361 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-1 | MIMAT0000416 | MIRT023750 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040586 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042011 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049532 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051871 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
