HCSGD entry for MPRIP


1. General information

Official gene symbolMPRIP
Entrez ID23164
Gene full namemyosin phosphatase Rho interacting protein
Other gene symbolsM-RIP MRIP RHOIP3 RIP3 p116Rip
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.43859660350.49353647280.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2855260210
GSE13712_SHEARUp0.1976126937
GSE13712_STATICUp0.0581986719
GSE19018Up0.2492106600
GSE19899_A1Down-0.2148648274
GSE19899_A2Up0.0276867181
PubMed_21979375_A1Down-0.2737499825
PubMed_21979375_A2Up0.1129664211
GSE35957Down-0.1976418410
GSE36640Up0.1563869328
GSE54402Down-0.2067293984
GSE9593Up0.0274359475
GSE43922Down-0.0489734026
GSE24585Up0.0215409126
GSE37065Down-0.3526241607
GSE28863_A1Up0.5318135830
GSE28863_A2Up0.3376717775
GSE28863_A3Up0.0283832789
GSE28863_A4Up0.1105002479
GSE48662Up0.2593827210

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-31-5pMIMAT0000089MIRT004977Luciferase reporter assay//qRT-PCRFunctional MTI19524507
hsa-miR-124-3pMIMAT0000422MIRT023094ProteomicsFunctional MTI (Weak)18668037
hsa-miR-1MIMAT0000416MIRT023650ProteomicsFunctional MTI (Weak)18668040
hsa-miR-1909-3pMIMAT0007883MIRT035803CLASHFunctional MTI (Weak)23622248
hsa-miR-1296-5pMIMAT0005794MIRT036110CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042870CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.