HCSGD entry for CIC


1. General information

Official gene symbolCIC
Entrez ID23152
Gene full namecapicua transcriptional repressor
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.25757034690.75565401010.95122000281.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0297979050
GSE13712_SHEARDown-0.3268689386
GSE13712_STATICUp0.0801200439
GSE19018Down-0.1867101125
GSE19899_A1Down-0.0379625163
GSE19899_A2Up0.2443180233
PubMed_21979375_A1Up0.0920980123
PubMed_21979375_A2Up0.8311586033
GSE35957Up0.0518220487
GSE36640Down-0.1741054542
GSE54402Up0.3349778223
GSE9593Up0.3236472838
GSE43922Up0.0341417277
GSE24585Down-0.0287905842
GSE37065Down-0.0022920348
GSE28863_A1Up0.1205276272
GSE28863_A2Up0.1323522695
GSE28863_A3Up0.2653658140
GSE28863_A4Up0.0367772570
GSE48662Down-0.1539807563

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-615-3pMIMAT0003283MIRT040419CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-3pMIMAT0002891MIRT040881CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041548CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.