HCSGD entry for PLXND1


1. General information

Official gene symbolPLXND1
Entrez ID23129
Gene full nameplexin D1
Other gene symbolsPLEXD1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisISSbiological_process
GO:0001569Patterning of blood vesselsIEAbiological_process
GO:0004872Receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneISScellular_component
GO:0007165Signal transductionIEAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0007416Synapse assemblyISSbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0017154Semaphorin receptor activityISSmolecular_function
GO:0030334Regulation of cell migrationISSbiological_process
GO:0032092Positive regulation of protein bindingIEAbiological_process
GO:0043542Endothelial cell migrationISSbiological_process
GO:0045765Regulation of angiogenesisISSbiological_process
GO:0060666Dichotomous subdivision of terminal units involved in salivary gland branchingIEAbiological_process
GO:0071526Semaphorin-plexin signaling pathwayISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.86960136390.01877837090.99999024730.2689224035

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3687788581
GSE13712_SHEARDown-0.3415286226
GSE13712_STATICDown-0.1497626080
GSE19018Up0.2116793795
GSE19899_A1Down-0.4694088237
GSE19899_A2Down-1.3859076818
PubMed_21979375_A1Down-1.1755337758
PubMed_21979375_A2Down-0.7293906622
GSE35957Down-0.2544527481
GSE36640Up0.2359409339
GSE54402Down-0.1856229717
GSE9593Down-0.1942671452
GSE43922Down-0.8813831245
GSE24585Down-0.0752842194
GSE37065Down-0.3792737951
GSE28863_A1Up0.6658512429
GSE28863_A2Up0.3944080954
GSE28863_A3Up0.1295870228
GSE28863_A4Down-0.1338517044
GSE48662Up0.2619850540

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT001523pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-335-5pMIMAT0000765MIRT017498MicroarrayFunctional MTI (Weak)18185580
hsa-miR-92b-3pMIMAT0003218MIRT040538CLASHFunctional MTI (Weak)23622248
hsa-miR-125b-5pMIMAT0000423MIRT045997CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.